STEM CELL THERAPY IN UROLOGY

  • Erectile dysfunction
  • Male infertility (upon prior approval by a doctor)
  • Malignant neoplasms
  • Critical disorders of blood coagulation system (platelet count ≤50×109)
  • Severe heart failure
  • Severe pulmonary failure (SpO2 <90%)
  • Kidney failure of IV-V degree
  • Infectious diseases in the acute phase (hepatitis C, hepatitis B, etc.)
  • Unstable hemodynamics, requiring correction with sympathomimetics
  • Terminal stage of incurable diseases
  • Acute stage of injuries or stroke

The therapeutic effect of stem cells is achieved due to their ability to differentiate and transdifferentiate into tissue-specific cells, to fuse with the resident cells, to secrete a wide array of paracrine factors in order to stimulate the survival and functional recovery of the resident cells or to regulate the local microenvironment or immune response.

Our Treatment Programs in Urology

  • 35 patient`s exams included
  • 2 doctor`s consultations
  • Up to 60 min of stem cells
  • Medical follow up for 1 year
  • Accommodation
  • 24/7 support
  • Translation
  • Transfer

Medical examination before stem cell therapy in Urology for men

Included:

  • General blood test with leukocyte formula
  • General blood test with leukocyte formula
    • Blood group (AB0) and Rh factor (Rh)
    • Coagulogram: prothrombin time (PT), prothrombin index (PTI), international normalized ratio (INR), percentage of prothrombin by Kvick, thrombin time (TT), activated partial thrombin time (APTT), fibrinogen (FB)
    • Lipid profile: cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, coefficient of atherogeny
    • Urine analysis general
    • HBs-antigen (HBsAg)
    • Hepatitis C virus, Ig total (anti-HCV)
    • Screening test for antibodies to HIV with IFA method
    • RMP with cardiolipin antigen for diagnosis of syphilis (RW)
    • Glucose of blood (venous/capillary blood)
    • Glycated hemoglobin (HbA1c)
    • Immunogram: subpopulations – CD3, CD4, CD8, CD22, CD16/56, immunoregulatory index Th/Ts; serum IgA, IgG, IgM. Phagocytic index, phagocytic number, NBT test. Individual sensitivity of lymphocytes to immunotropic drugs
    • Herpes simplex virus (HSV) 1/2 types, IgG, IgM
    • Epstein Barr virus VCA (EBV VCA), IgG, IgM
    • Cytomegalovirus (CMV), IgG, IgM
    • Toxoplasma gondii, IgG, IgM
    • Human chorionic gonadotropin (beta-hCG) total
    • Prostate-specific antigen total (Total PSA)
    • Kidney Function Test Complex: urea, uric acid, creatinine, potassium
    • Liver Function Test Complex: bilirubin fractionally, ALT, AST,  ALP, GGT
    • Alpha-fetoprotein (AFP)
    • Luteinizing hormone (lutropin, LH)
    • Follicle-stimulating hormone (follitropin, FSH)
    • Thyroid-stimulating hormone (thyrotropin/TSH)
    • Testosterone free index (testosterone total, testosterone-estradiol binding globulin, index calculation)
    • Testosterone free
    • Estradiol (E2)
    • Prolactin (mammotropin)
    • Electrocardiogram (ECG)
    • Abdomen ultrasound examination
    • Kidneys & bladder ultrasound examination
    • Thyroid gland ultrasound examination
    • Scrotum ultrasound examination with Doppler of vessels
    • Penis ultrasound examination with Doppler of vessels – in case of erectile dysfunction
    • Prostate transrectal ultrasound examination
    • Sexually transmitted infections Advanced Complex: Chlamydia, Ureaplasma, Mycoplasma hominis, Mycoplasma genital, Trichomonas (PCR, quantitative analysis), bacterial cultures of urogenital secretions with sensitivity to antibacterial preparations
    • Androflor Screen: Investigation of biocenosis of the urogenital tract, PCR (urine – if it is impossible to take a scam)
    • Androflor: Investigation of biocenosis of the urogenital tract, PCR (ejaculate, secret of the prostate, scraping from the urethra)
    • Consultation of therapist (primary)
    • Consultation of urologist (primary)
    • Semen analysis – in case of infertility
    • HBA-test – in case of infertility
    • Sperm oxidative stress test (ROS-test) – in case of infertility
    • MAR-test (determination of anti-sperm antibodies) – in case of infertility
    • Karyotyping of the patient – in case of azoospermia
    • DNA diagnostics of Y-chromosome microdeletion – in case of azoospermia
    • DNA diagnostics of mucoviscidosis – in case of azoospermia

 

  • Testicular aspiration biopsy (TESA) – if medically required
  • Semen Culture – if medically required

 

  • Postorgasmic urine analysis – if medically required

 

The list of examination can be modified or enlarged in accordance with doctor’s recommendations.

 

Possible methods of cellular material administration:

  • Intravenously
  • Intracavernously
  • Other methods of local administration

 

Quantity of cell material for Standard program in Urology: up to 60 mln of stem cells.

  • 35 patient`s exams included
  • 2 doctor`s consultations
  • Up to 60 min of stem cells
  • Medical follow up for 1 year
  • Accommodation
  • 24/7 support
  • Translation
  • Transfer

Medical examination before stem cell therapy in Urology for men

Included:

  • General blood test with leukocyte formula
  • General blood test with leukocyte formula
    • Blood group (AB0) and Rh factor (Rh)
    • Coagulogram: prothrombin time (PT), prothrombin index (PTI), international normalized ratio (INR), percentage of prothrombin by Kvick, thrombin time (TT), activated partial thrombin time (APTT), fibrinogen (FB)
    • Lipid profile: cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, coefficient of atherogeny
    • Urine analysis general
    • HBs-antigen (HBsAg)
    • Hepatitis C virus, Ig total (anti-HCV)
    • Screening test for antibodies to HIV with IFA method
    • RMP with cardiolipin antigen for diagnosis of syphilis (RW)
    • Glucose of blood (venous/capillary blood)
    • Glycated hemoglobin (HbA1c)
    • Immunogram: subpopulations – CD3, CD4, CD8, CD22, CD16/56, immunoregulatory index Th/Ts; serum IgA, IgG, IgM. Phagocytic index, phagocytic number, NBT test. Individual sensitivity of lymphocytes to immunotropic drugs
    • Herpes simplex virus (HSV) 1/2 types, IgG, IgM
    • Epstein Barr virus VCA (EBV VCA), IgG, IgM
    • Cytomegalovirus (CMV), IgG, IgM
    • Toxoplasma gondii, IgG, IgM
    • Human chorionic gonadotropin (beta-hCG) total
    • Prostate-specific antigen total (Total PSA)
    • Kidney Function Test Complex: urea, uric acid, creatinine, potassium
    • Liver Function Test Complex: bilirubin fractionally, ALT, AST,  ALP, GGT
    • Alpha-fetoprotein (AFP)
    • Luteinizing hormone (lutropin, LH)
    • Follicle-stimulating hormone (follitropin, FSH)
    • Thyroid-stimulating hormone (thyrotropin/TSH)
    • Testosterone free index (testosterone total, testosterone-estradiol binding globulin, index calculation)
    • Testosterone free
    • Estradiol (E2)
    • Prolactin (mammotropin)
    • Electrocardiogram (ECG)
    • Abdomen ultrasound examination
    • Kidneys & bladder ultrasound examination
    • Thyroid gland ultrasound examination
    • Scrotum ultrasound examination with Doppler of vessels
    • Penis ultrasound examination with Doppler of vessels – in case of erectile dysfunction
    • Prostate transrectal ultrasound examination
    • Sexually transmitted infections Advanced Complex: Chlamydia, Ureaplasma, Mycoplasma hominis, Mycoplasma genital, Trichomonas (PCR, quantitative analysis), bacterial cultures of urogenital secretions with sensitivity to antibacterial preparations
    • Androflor Screen: Investigation of biocenosis of the urogenital tract, PCR (urine – if it is impossible to take a scam)
    • Androflor: Investigation of biocenosis of the urogenital tract, PCR (ejaculate, secret of the prostate, scraping from the urethra)
    • Consultation of therapist (primary)
    • Consultation of urologist (primary)
    • Semen analysis – in case of infertility
    • HBA-test – in case of infertility
    • Sperm oxidative stress test (ROS-test) – in case of infertility
    • MAR-test (determination of anti-sperm antibodies) – in case of infertility
    • Karyotyping of the patient – in case of azoospermia
    • DNA diagnostics of Y-chromosome microdeletion – in case of azoospermia
    • DNA diagnostics of mucoviscidosis – in case of azoospermia

 

  • Testicular aspiration biopsy (TESA) – if medically required
  • Semen Culture – if medically required

 

  • Postorgasmic urine analysis – if medically required

 

The list of examination can be modified or enlarged in accordance with doctor’s recommendations.

 

Possible methods of cellular material administration:

  • Intravenously
  • Intracavernously
  • Other methods of local administration

 

Quantity of cell material for Advanced program in Urology: up to 120 mln of stem cells.

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